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doxycycline Home > Archives > Volume 18, No 1 (2020) > Article

DOI: 10.14704/nq.2020.18.1.NQ20102

Thiazole Amide Derivatives (Synthesis, Spectral Investigation, Chemical Properties, Antifungal Assay)

Alaa Jawad Kadhim, Jalal Hasan Mohammed, Dr. Nagham Mahmood Aljamali

Abstract

The thiazole nucleus structure is essential unit in biologically important molecules, and various pharmaceutically active thiazole analogs have been conveyed., The versatility of thiazole unit demonstrated via the fact which it is an important part from penicillin corebesides some of its products that have appeared antibacterial (sulfazole), antifungal (abafungin), antihistaminic. The scope of this paper is synthesis of series new thiazole-amide derivatives via numerous types of reactions like (azotation reaction, coupling reaction, substitution reaction,…).Thiazole derivatives were confirmed via many spectral techniques (FT.IR,H.NMR,C.NMR)–spectrophotometric, other chemical characterization, with evaluation of formatted compounds as antifungal compounds.

Keywords

Thiazole Amide Derivatives (Synthesis, Spectral Investigation, Chemical Properties, Antifungal Assay)

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