DOI: 10.14704/nq.2018.16.6.1573

Cause Analysis and Control of Thyroid Disease Based on Cognitive Behavior Science

Yan Zhao, Jiajing Le, LiFeng Zhu, Ming Zuo


Due to the accelerated pace of life, thyroid function problems have become increasingly prominent, affecting human health. With ERP method, this study deals with the cognitive function of thyroid patients by comparing the data between thyroid patients and healthy people based on signal task and game experiment. The results show that there are significant differences in the accuracy rate and the error rate between the two groups in the signal task experiment and the healthy group performs better than the hyperthyroidism group. In the first three stages of the game experiment, the net score of the hyperthyroidism group increases more than that of the healthy control group and the executive function of the hyperthyroidism subjects is significantly impaired. For the health control group, FRN difference wave has certain statistical significance under different feedback intensities, but the FRN difference is not obvious for the hyperthyroidism group. The sensitivity of hyperthyroidism patient reduces accordingly, thus their response to the stimulus with high and to stimulus with low feedback intensity tends to be similar. In the stop signal task, the N2 amplitude of patients with hyperthyroidism is significantly lower than that of the healthy control group, and the impairment of prefrontal lobe function is associated with the decrease of N2 amplitude, especially in patients with hyperthyroidism, which is accompanied by the decrease of frontal lobe metabolism.


Cognitive Behavior, Thyroid Disease, Brain Mechanism

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