DOI: 10.14704/nq.2018.16.6.1635

Neural Mechanism for Spatial Memory Exposed to Mozart Music

Qinglan Du, Bing Wu


In order to further investigate the structural characteristics of some music tracks that may produce the "Mozart effect", this paper describes the key musical elements of "Mozart effect". Mozart K.448 and reversed Mozart K.448 are chosen as music stimulus materials to examine ethological changes of rodents and students. It has been proven that there is indeed the "Mozart effect". We also apply molecular biology techniques to carry out profound discussion on production mechanism of "Mozart effect". The results show that in hippocampus region, with the extension of music exposure time, the average optical density of the Mozart group is significantly higher than that of the blank group in appropriate development phase. The protein expression levels of BDNF/TrkB in the hippocampus and in auditory cortex regions of rats exposed to Mozart music in different development phases have been significantly increased, which coincides with ethological findings.


Music, Spatial Memory, Brain Mechanism

Full Text:



Angelucci F, Ricci E, Padua L, Sabino A, Tonali PA. Music exposure differentially alters the levels ofbrain-derived neurotrophic factor and nerve growth factor in the mouse hypothalamus. Neuroscience letters 2007; 429(2): 152-55.

Crncec R, Wilson SJ, Prior M. No evidence for the Mozart effect in children. Music Perception 2006; 23(4): 305-18.

Cuervo G, Garcia-Vidal C, Nucci M, Puchade F, Fernández-Ruiz M. Breakthrough candidemia in the era of broad-spectrum antifungal therapies. Clinical Microbiology & Infection 2016; 22(2): 181-88.

Ivanov VK, Geake JG. The Mozart Effect and primary school children. Psychology of Music 2003; 31(4): 405-13.

Jones MH, Estell DB. Exploring the Mozart effect among high school students. Psychology of Aesthetics Creativity & the Arts 2007; 1(4): 219-24.

McKelvie P, Low. Listening to Mozart does not improve children’s spatial ability: Final curtains for the Mozart effect. British Journal of Developmental Psychology 2002; 20: 241-58.

Nantais KM, Schellenberg EG. The Mozart effect: an artifact of preference. Psychological Science 1999; 10: 370-73.

Steele KM. Do rats show a Mozart effect. Music Perception 2003; 21: 251-65.

Supporting Agencies

| NeuroScience + QuantumPhysics> NeuroQuantology :: Copyright 2001-2017