DOI: 10.14704/nq.2016.14.1.874

Is it Quantum Sentience or Quantum Consciousness? A Review of Social Behaviours Observed in Primitive and Present-Day Microorganisms

Contzen Pereira


Social and intelligent behavioural designs have been observed in primitive and present day microorganisms in all three kingdoms of life. These behavioural patterns help microorganisms, to understand, evaluate and judge their constantly varying environment. Behaviour is represented as conscious moment, which occurs due to an event, which may be intentional or unintentional. Microorganisms have the capability of displaying behaviours, which can be compared to cognitive actions of the neural system in higher organisms. This review is a collection of social behaviours observed in present-day microorganisms as well as predicted behaviours in microfossils that have been studied so far. The intent of this review is to prove the origin and existence of consciousness or sentient awareness in microorganisms based on which these social behaviours originated and its comparison to multifaceted conscious behaviours observed in higher beings; its correlation to quantum generated consciousness which enables organisms to understand and judge perceptions, which gives the organism a prospect to behave as per will.


consciousness; sentience; quantum; behaviour; archaea; bacteria; uukarya; microorganisms

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Adamatzky A, Armstrong R, Jones J, Gunji Y. On creativity of slime mould. Int J Gen Sys 2013; 42: (5) 441-457, doi:10.1080/03081079.2013.776206.

Anderson OR. Comparative Protozoology: Ecology, Physiology, Life History. Springer-Verlag; 1 ed. 1998.

Arkin A, Ross J, McAdams HH. Stochastic Kinetic Analysis of Developmental Pathway Bifurcation in Phage λ-Infected Escherichia coli Cells. Genetics 1998; 149(4): 1633-1648.

Baluška F, & Mancuso S. Deep evolutionary origins of neurobiology. Turning the essence of ‘neural’ upside-down. Commun. Integr. Biol. 2009; 2(1): 60–65.

Bardy SL, Ng SYM, Jarrell KF. Prokaryotic motility structures. Microbiol 2003; 149 (2): 295-304. doi: 10.1099/mic.0.25948-0.

Bhattacharya P, Xu J, Varo G, Marcy DL, Birge RR. Monolithically integrated bacteriorhodopsin-GaAs field-effect transistor photoreceiver. Opt Lett 2002; 27(10): 839-41.

Berelson WM, Corsetti FA, Pepe-Ranney C, Hammond DE, Beaumont W, Spear JR. Hot spring siliceous stromatolites from Yellowstone National Park: assessing growth rate and laminae formation. Geobiol 2011; 9: 411–424.

Berleman JE, Scott J, Chumley T, Kirby JR. (2008). Predataxis behavior in Myxococcus Xanthus. PNAS 2008; 105 (44): 17127–17132. doi_10.1073_pnas.0804387105.

Bertelson P, Hutton R, McClure K. (Workshop Overview). The Social Biology of Microbial Communities: Workshop Summary. Institute of Medicine (US) Forum on Microbial Threats. Washington (DC): National Academies Press (US). 2012.

Brown JR & Doolittle WF. Archaea and the Prokaryote-to-Eukaryote Transition. Microbiol Mol Biol Rev 1997; 61: 456 – 502.

Bonner JL. The Social Amoebae: The Biology of Cellular Slime Molds. Princeton University Press, 2008.

Bonner JT. First Signals: The Evolution of Multicellular Development. Princeton University Press, 2001.

Bourret RB & Stock AM. Molecular Information Processing: Lessons from Bacterial Chemotaxis. J Biol Chem 2002; 277: 9625-9628. doi: 10.1074/jbc.R100066200.

Budrene E & Berg H. Complex patterns formed by motile cells of Escherichia coli. Nature 1991; 349: 630-633.

Cecchini DA, Laville E, Laguerre S, Robe P, Leclerc M, Dore J. et al., Functional metagenomics reveals novel pathways of prebiotic breakdown by human gut bacteria. PloS One 2013; 8 (9). doi: 10.1371/journal.pone.0072766.

Christensen BE. The role of extracellular polysaccharides in biofilms. J Biotech 1989; 10: 181-202.

Clark A. Phenomenal consciousness so-called. In Werner Backhaus, (ed), Neuronal Coding of Perceptual Systems. New Jersey: World Scientific, Series on Biophysics and Biocybernetics 2001; 9: 405 -422.

Clark KB. Social biases determine spatiotemporal sparseness of ciliate mating heuristics. Commun Integr Biol 2012; 5(1): 3–11.

Corsetti FA, Awramik SM, Pierce D. A complex microbiota from snowball Earth times: microfossils from the Neoproterozoic Kingston Peak Formation, Death Valley, USA. Proc Natl Acad Sci 2003; 100(8): 4399-4404.

Crespi BJ. The evolution of social behavior in microorganisms. Trends Ecol Evol 2001; 16: 178–183.

Crisp A, Boschetti C, Perry M, Tunnacliffe A, Micklem G. Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes. Genome Biol 2015; 16: 50. doi: 10.1186/s13059-015-0607-3.

Dao DN, Kessin RH, Ennis HL. Developmental cheating and the evolutionary biology of Dictyostelium and Myxococcus. Microbiol 2000; 146 (7): 1505-1512.

Deep A, Chaudhary U, Gupta V. Quorum sensing and Bacterial Pathogenicity: From Molecules to Disease. J Lab Physicians 2011; 3(1): 4–11. doi: 10.4103/0974-2727.78553.

DeLong EF. Oceans of Archaea. ASM News 2003; 69: 10.

Diehn B. Phototaxis and sensory transduction in Euglena. Science 1973; 14: 181(4104), 1009-1015.

Dinan TG, Stilling RM, Stanton C, Cryan JF. Collective unconscious: How gut microbes shape human behaviour. J Psych Res 2015; 63: 1–9. doi:10.1016/j.jpsychires.2015.02.021.

Durmus T & Balkis N. Tintinnid (Protozoa: Ciliophora) species in the Gulf of Gemlik and some ecological properties of the environment. Fresenius Environ Bull 2014; 23 (12): 2991 – 2997.

Dussutour A, Latty T, Beekman M, Simpson SJ. Amoeboid organism solves complex nutritional challenges. PNAS 2010; 107 (10). doi: 10.1073/pnas.0912198107.

Dyall-Smith ML, Pfeiffer F, Klee K, Palm P, Gross K, Schuster SC, Rampp M, Oesterhelt D. Haloquadratum walsbyi: Limited Diversity in a Global Pond. PLoS One 2011; 6 (6): 1-23. doi:10.1371/journal.pone.0020968.

Eckburg PB, Lepp PW, Relman DA. Archaea and Their Potential Role in Human Disease. Infect Immun 2003; 71 (2): 591-596. doi: 10.1128/IAI.71.2.591-596.

England JC, Gober JW. Cell cycle control of cell morphogenesis in Caulobacter. Curr Opin Microbiol 2001; 4(6):674-80.

Fenchel T & Finlay B. Free-Living Protozoa with Endosymbiotic Methanogens. J.H.P. Hackstein (ed.), (Endo)symbiotic Methanogenic Archaea, Microbiology Monographs 2010; 19, doi: 10.1007/978-3-642-13615-3_1, # Springer-Verlag Berlin Heidelberg.

Fenchel T & Finlay B. Oxygen and the Spatial Structure of Microbial Communities. Biol Rev 2008; 83: 553–569. doi:10.1111/j.1469-185X.2008.00054.x.

Fiore CL, Jarett JK, Olson ND, Lesser MP. Nitrogen fixation and nitrogen transformations in marine symbioses. Trends in Microbiology 2010; 18 (10): 455–463.

Ford BJ. Are cells ingenious? Microscope 2004; 52:3/4, 135 -144.

Forterre P. The Common Ancestor of Archaea and Eukarya Was Not an Archaeon. Archaea 2013; 18.

Gibbs KA, Urbanowski ML, Greeberg EP. Genetic determinants of self identity and social recognition in bacteria. Science. 2008; 321(5886): 256–259 doi: 10.1126/science.1160033.

Gregor T, Fujimoto K, Masaki N, Sawai S. The Onset of Collective Behavior in Social Amoebae. Science 2010; 328 (5981). 1021-1025. DOI: 10.1126/science.1183415.

Godin A, McLaughlin JW, Webster KL, Packalen M, Basiliko N. Methane and methanogen community dynamics across a boreal peatland nutrient gradient. Soil Biol Biochem 2012; 48: 96–105. doi:10.1016/j.soilbio.2012.01.018.

Goo E, Majerczyk CD, Hyung An A, Chandler JR, Seo Y, Ham H, Lim JY, Kim H., Lee B, Jang MS, Greeberg EP, Hwang I. Bacterial quorum sensing, cooperativity, and anticipation of stationary-phase stress. Proc Natl Acad Sci USA 2012; 109(48); 19775–19780. doi: 10.1073/pnas.1218092109.

Griffin AS, West SA, Buckling A. Cooperation and competition in pathogenic bacteria. Nature 2004; 430: 1024–1027.

Hameroff S. How quantum brain biology can rescue conscious free will. Front Integr Neurosci 2012; 6: 93. doi: 10.3389/fnint.2012.00093.

Hameroff, S. & Penrose, R. Consciousness in the universe. A review of the ‘Orch OR’ theory. Phys Life Rev 2014; 11: 39–78.

Han J, Hou J, Liu H, Cai S, Feng B, Zhou J, Xiang H. Wide Distribution among Halophilic Archaea of a Novel Polyhydroxyalkanoate Synthase Subtype with Homology to Bacterial Type III Synthases. Appl Environ Microbiol. 2010; 76(23): 7811–7819. doi: 10.1128/AEM.01117-10.

Harris JK, Caporaso JG, Walker JJ, Spear JR, Gold NJ, Robertson CE, Hugenholtz P, Goodrich J, McDonald D, Knights D, Marshall P, Tufo H, Knight R, Pace NR. Phylogenetic stratigraphy in the Guerrero Negro hypersaline microbial mat. The ISME Journal 2012; 7: 50–60. doi:10.1038/ismej.2012.79.

Harvey AW & Bovell NK. Spontaneous alternation behavior in Paramecium. Learn Behav 2006; 34(4): 361-5.

Herzog B & Wirth R. Swimming Behavior of Selected Species of Archaea. App Environ Microbiol 2012; 78(6):1670-4. doi: 10.1128/AEM.06723-11.

Holmes SJ. The behavior of Loxophyllum and its relation to regeneration. J Exp Zoo 2005; 4(3):399–418. DOI: 10.1002/jez.1400040304.

Jahnert RJ & Collins LB. Characteristics, distribution and morphogenesis of subtidal microbial systems in Shark Bay, Australia. Marine Geology 2012; 303–306, 115–136.

Javor B, Requadt C, Stoeckenius W. Box-shaped halophilic bacteria. J Bacteriol 1982; 151(3): 1532–1542.

Jennings HS. Behavior of the Lower Organisms. 1905/1962. Bloomington: Indiana University Press.

Jensen DD. A Theory of the Behavior of Paramecium aurelia and Behavioral Effects of Feeding, Fission, and Ultraviolet Microbeam Irradiation. Behaviour 1959; 15(1/2): 82-122.

Jeon KW. The large, free-living amoebae: wonderful cells for biological studies. J Eukaryot Microbiol 1995; 42: 1–7.

Kaine BP. Structure of the archaebacterial 7S RNA molecule. Molecular and General Genetics 1990; 221(3): 315-321.

King C. Cosmological foundations of Consciousness. J Cosmol 2011; 14. Accessed on 22nd May 2015.

Latty T & Beekman M. Food quality and the risk of light exposure affect patch-choice decisions in the slime mold Physarum polycephalum. Ecology 2010; 91(1): 22–27.

Lepot K, Benzerara K, Brown GE, Philippot P. Microbially influenced formation of 2.7 billion-year-old stromatolites. Nature Geoscience 2008; 1 (2): 118–21.

Low P. Consciousness in human and non-human animals. The Francis Crick Memorial Conference, eds Panksepp J, et al., (Cambridge, UK). 2012. Available at http:// Accessed April 10, 2015.

Lyon P. The cognitive cell: bacterial behavior reconsidered. Front Microbiol 2015; 6: 264. doi: 10.3389/fmicb.2015.00264.

Lyon P. From quorum to cooperation: lessons from bacterial sociality for evolutionary theory. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 2007; 38(4): 820–833.

Margulis L & Sagan D. What is life? The Eternal Enigma. University of California Press, 1995.

Marijuán PC, del Moral R, Navarro J. On eukaryotic intelligence: signaling system's guidance in the evolution of multicellular organization. Biosystems 2013; 114(1): 8-24. doi: 10.1016/j.biosystems.2013.06.005.

Mast SO & Hahnert WF. Feeding, Digestion, and Starvation in Amoeba proteus (Leidy). Physiological Zoology 1935; 8: (3), 255-272.

Maturana HR. Biology of Cognition. Biological Computer Laboratory Research Report BCL 9.0. Urbana IL: University of Illinois, 1970. As Reprinted in: Autopoiesis and Cognition: The Realization of the Living. Dordecht: D. Reidel Publishing Co. 1980; 5: 58.

Murray JW. Unravelling the life cycle of Polystomella crispa: the roles of Lister, Jepps and Myers J. Micropalaeontology 2012; 31:121-129, doi: 10.1144/0262-821X11-034.

Nadell C, Xavier JB, Kevin R, Foster KR. The socio-biology of biofilms. FEMS Microbiol Rev 2009; 1: 19.

Nadell CD, Bassler BL, Levin SA. Observing bacteria through the lens of social evolution. J Biol 2008; 7: 27. doi:10.1186/jbiol87.

Nakagaki T, Yamada H, T´oth A. Path finding by tube morphogenesis in an amoeboid organism. Biophys Chem 2001; 92: 47-52.

Neilands JB. Siderophores: Structure and Function of Microbial Iron Transport Compounds. J Biol Chem 1995; 270 (45): 26723 – 26726. doi:10.1074/jbc.270.45.26723.

Ng W & Bassler BL. Bacterial quorum-sensing network architectures. Annu Rev Genet 2009; 43:197-222. doi: 10.1146/annurev-genet-102108-134304.

Nicolaus B, Schiano MV, Lama L, Poli A, Gambacorta A. Polysaccharides from extremophilic microorganisms. Origins of Life and Evolution of Biospheres 2003; 34: 159–169.

Nisbet EG & Sleep NH. The habitat and nature of early life. Nature 2001; 409: 1083-1091 doi:10.1038/35059210.

Nisbet EJ, Cann JR, Lee C, Dover V. Origins of photosynthesis. Nature 1995; 373: 479 – 480. doi:10.1038/373479a0.

Noireau F, Diosque P, Jansen AM. Trypanosoma cruzi: adaptation to its vectors and its hosts. Vet Res 2009; 40(2): 26. doi: 10.1051/vetres/2009009.

Ochman H, Lawrence JG, Groisman EA. Lateral gene transfer and the nature of bacterial innovation. Nature 2000; 405: 299 – 304.

Oren A. Bioenergetic aspects of halophilism. Microbiol. Mol Biol Rev 1999; 63, 334–348.

Parson CW. Some observations on the behaviour of Amoeba proteus. Quarterly Journal of Microscopical Sciences 1926; 2-70: 629-646.

Pereira C. Cytoskeleton and Consciousness: An Evolutionary Based Review. NeuroQuantology 2015 a; 13 (2): 232-239.

Pereira C. Quantum Consciousness in Animals. Journal of Metaphysics and Connected Consciousness 2015 b (August 2015).

Pikuta EV, Hoover RB, Tang J. Microbial extremophiles at the limits of life. Crit Rev Microbiol 2007; 33 (3): 183–209. doi:10.1080/10408410701451948.

Popat R, Cornforth DM, McNally L, Brown SP. Collective sensing and collective responses in quorum-sensing bacteria. J R Soc Interface 2015; 12 (103): DOI: 10.1098/rsif.2014.0882.

Prosser JI & Nicol GW. Relative contributions of archaea and bacteria to aerobic ammonia oxidation in the environment. Environ Microbiol 2008; 210(11): 2931-41. doi: 10.1111/j.1462-2920.2008.01775.x.

Radnitzky G, Bartley WW, Popper K. Evolutionary Epistemology, Rationality, and the Sociology of Knowledge. 1993. Open Court Publishing Company; Third Printing edition (March 1, 1993).

Ramakrishna BS. Role of the gut microbiota in human nutrition and metabolism. J Gastroenterol Hepatol 2013; 28 (4): 9–17.

Reid CR, Beekman M, Latty T, Dussutour, A. Amoeboid organism uses extracellular secretions to make smart foraging decisions. Behavioral Ecology 2013; 24 (4): 812-818. doi: 10.1093/beheco/art032.

Saunders NF, Thomas T, Curmi PM, Mattick JS, Kuczek E, Slade R, Davis J, Franzmann PD. et al. Mechanisms of thermal adaptation revealed from the genomes of the Antarctic Archaea Methanogenium frigidum and Methanococcoides burtonii. Genome Research 2003; 13: 1580-1588.

Schonfeld J & Nunberger L. Seasonal dynamics and decadal changes of benthic foraminiferal assemblages in the western Baltic Sea (NW Europe). J Micropalaeontology 2007; 26: 47-60. doi: 10.1144/jm.26.1.47.

Shapiro JA. Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology. Studies in History and Philosophy of Biological and Biomedical Sciences 2007; 38: 807–819.

Shiono H & Naitoh Y. Cellular contraction precedes membrane depolarization in Vorticella convallaria. J Exp Biol 1997; 200: 2249–2261.

Sirota-Madi A, Olender T, Helman Y, Ingham C, Brainis I, Roth D, Hagi, E, Brodsky L, Leshkowitz D, Galatenka V, Nikolaev V, Mugasimangalam RC, Bransbury-Zabary S, Gutnick DL, Lancet D, Ben-Jacob E. Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments. BMC Genomics 2010; 11: 710. doi:10.1186/1471-2164-11-710.

Smetia E, Kormasb K, Spatharis S. A non-phylogenetic alpha diversity approach on prokaryotic community structure in aquatic systems. Ecological Indicators 2013; 29: 361–366.

Smith RS & Iglewski BH. Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target. J Clin Invest 2003; 112(10): 1460-1465. doi:10.1172/JCI20364.

Solari CA. The flagellar photoresponse in Volvox species (Volvocaceae Chlorophyceae). J Phycol 2011; 47: 580–583.

Staddon JER. Adaptive Behavior and Learning. 1983, Cambridge University Press.

Stoodley P, Lewandowski Z, Boyle JD, Lappin-Scott HM. The formation of migratory ripples in a mixed species bacterial biofilm growing in turbulent flow. Environ Microbiol 1999; 1(5): 447-455.

Strauss G, Eisenreich W, Bacher A, Fuchs G. 13C-NMR study of autotrophic CO2 fixation pathways in the sulfur-reducing Archaebacterium Thermoproteus neutrophilus and in the phototrophic Eubacterium Chloroflexus aurantiacus. European J Biochem 1992; 204: 853–866.

Sundberg S, Bogomolni RA, Spudichi JL. Selection and properties of phototaxis-deficient mutants of Halobacterium halobium. J Bact 1985; 164 (1): 282-287.

Travisano M & Velicer GJ. Strategies of microbial cheater control. Trends Microbiol 2004; 12: 72–78.

Trewavas AJ & Baluska F. The ubiquity of consciousness. The ubiquity of consciousness, cognition and intelligence in life. EMBO Rep 2011; 12(12): 1221–1225. doi: 10.1038/embor.2011.218.

Velicer GJ. Social strife in the microbial world. Trends Microbiol. 2003; 11, 330–337.

Velicer GJ, Kroos L, Lenski RE. Developmental cheating in the social bacterium Myxococcus Xanthus. Nature 2000; 404 (6778): 598-601.

Visick KL & Fuqua C. Decoding Microbial Chatter: Cell-Cell Communication in Bacteria. J Bacteriol 2005; 187(16): 5507-5519. doi: 10.1128/JB.187.16.5507-5519.2005.

Wadhams GH & Armitage JP. Making sense of it all: bacterial chemotaxis. Nature Reviews Molecular Cell Biology 2004; 5: 1024-1037. doi:10.1038/nrm1524.

Wang WW, Knopf GK, Bassi AS. Photoelectric properties of a detector based on dried bacteriorhodopsin film. Biosensors and Bioelectronics 2006a; 21 (7): 1309-1319.

Wang W, Lai H, Hsueh P, Chiou RY, Lin S, Liaw S. Inhibition of swarming and virulence factor expression in Proteus mirabilis by resveratrol. J Med Microbiol 2006b; 55 (10): 1313-1321. doi: 10.1099/jmm.0.46661-0.

Westerhoff HV, Brooks AN, Simeonidis E, Garcia-Contreras R, He F, Boogerd FC, Jackson VJ, Goncharuk V, Kolodkin A. Macromolecular networks and intelligence in microorganisms. Front Microbiol 2014; 5: 379. doi: 10.3389/fmicb.2014.00379.

Young KD. The Selective Value of Bacterial Shape. Microbiol Mol Biol Rev 2006; 70(3): 660–703. doi: 10.1128/MMBR.00001-06.

Zhang JY, Chen WL, Zhang CC. hetR and patS, two genes necessary for heterocyst pattern formation, are widespread in filamentous nonheterocyst-forming cyanobacteria. Microbiol 2009; 155 (5): 1418-1426.

Zhang Z. Solar cyclicity in the Precambrian microfossil record. Paleontology 1986; 29 (1): 101 – 111.

Zhao K, Liu M, Burgess RR. Adaptation in bacterial flagellar and motility systems: from regulon members to ‘foraging’-like behavior in E. Coli. Nucleic Acids Res 2007; 35(13): 4441–4452. doi: 10.1093/nar/gkm456.

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