Introduction: Gliomas are primary brain tumors arising from glial cells, categorized into low-grade and high-grade forms based on their growth characteristics. They are more prevalent in adults and are a leading cause of cancer-related deaths among young adults. Recent advancements in classification techniques, incorporating molecular features, aim to enhance survival prediction and guide treatment decisions. Diffuse gliomas, particularly glioblastoma, are the most lethal subtype of central nervous system neoplasms. Molecular and genetic indicators have significant implications for prognosis and treatment, complementing traditional histopathological assessments. Case description: A case study of a 35-year-old woman with symptoms suggestive of a high-grade glioma is presented. Imaging revealed a mass lesion in the brain, necessitating surgical resection followed by postoperative management. The case underscores the challenges in diagnosing and managing gliomas and the importance of a multidisciplinary approach for optimal patient care. Discussion: Highlights the aggressive nature of gliomas and the importance of complete surgical resection for improved outcomes, especially in high-grade tumors. Emerging therapies such as immunotherapy and targeted molecular treatments show promise in enhancing treatment effectiveness. Collaborative efforts among healthcare professionals are crucial for advancing the understanding and management of gliomas.

Gliomas, primary brain tumors, glial cells, classification techniques, brain mass, surgical resection, immunotherapy, multidisciplinary approach, healthcare collaboration.