Volume 20 No 1 (2022)
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“Assessment of Heapatoprotective Potential by Using Different Strategies; a Review”
Revendra Parganiha
Abstract
The liver excretes bile and regulates the bulk of blood chemical levels. This facilitates the liver's ability to eliminate waste. All blood that exits the stomach and intestine is processed by the liver. The liver breaks down, regulates, and creates nutrients while processing this blood. Additionally, it metabolizes drugs to lessen their toxicity or increase their ability to be absorbed by the body. Various models for assessing hepatoprotective activity in vitro, in vivo and ex vivo can be found in a literature review.This review's objective is to outline the key benefits and drawbacks of each model, as well as the most common hepatotoxic substances-carbon tetra chloride, paracetamol, ethanol, d-galactosamine, and thioacetamide and biochemical parameters that can be used to compare the different models' liver damage.
Keywords
Hepatoprotective, heapatotoxicity, carbon tetrachloride.
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