Volume 20 No 22 (2022)
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“Formulation and Evaluation of Fast Dissolving Herbal Tablet From Dyerophytum Indicum Bark Extract”
Dattaprasad N. Vikhe, Rahul Kunkulol, Ravindra S Jadhav, Ganesh S Shinde
The aim of the present work is to formulate a fast release tablet containing herbal extract of Dyerophytum indicum as drug, by direct compression method. Tablets contain super-disintegrant which disintegrate and dissolve fast and give its rapid onset of action. The effect of various superdisintegrants on the disintegration was studied. Croscarmelose sodium (CCS), crospovidone (CP) and starch were selected as a superdisintegrants.. Infrared (IR) spectroscopy, performed to check out compatibility of drug extracts and the excipients. Powder blend of drug and excipients was investigated for the micromeritic properties. Evaluation of FDT was carried out for appearance, hardness, thickness, and weight variation, friability, and disintegration time and dissolution studies. Dissolution studies were carried out of all the formulations (F1 – F6). The F6 formulation significant result and dissolution release than other formulation batches.
Dyerophytum indicum, superdisintegrants,herbal extract,fast dissolving tablet.
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