To investigate if a relationship exists between idiopathic intracranial hypertension and widened interpalpebral fissures. This is a retrospective case-control study comparing eyelid measurements, including margin-reflex distance and palpebral fissure distance, in diagnosed patients with hypertension of idiopathic intracranial according to International Classification of Headache Disorders (ICDH) 3-beta criteria and in age-matched controls. Patients with hypertension of idiopathic intracranial were 42 and 120 controls were included. All patients were Middle-East Caucasians and the mean age in the disease group was 34 ± 7 years and in the control group 35 ± 6 years (p=0.28). The disease group had 81% female patients compared to 60% female patients in control group (p=0.01). For group of disease, mean margin-reflex distance (5.36 ± 0.31 mm) and mean palpebral fissure distance (10.84 ± 0.75 mm) values were significantly higher compared to the corresponding values in control group (4.01 ± 0.26 mm and 9.39 ± 0.62 mm, respectively) (p<0.01 for both comparisons).

Debilitating Disease, Hypertension, Idiopathic Intracranial.