Volume 22 No 2 (2024)
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A Comparative Analysis of Radiological and Histopathological findings in Space-Occupying Lesions of Spinal Cord
Dr Govinddas G Akbari, Dr Kokkula Vishal Kumar, Dr Abhijit Patil, Dr Sylvester Noeldoss Lazarus
Abstract
Introduction: Spinal tumors typically manifest early with signs of compression and/or invasion, highlighting the critical importance of timely management to prevent irreversible neurological deficits. The aim of this study was to assess the diagnostic efficacy of radiology in accurately establishing a preliminary working diagnosis for various types of spine tumors.
Materials and Methods: This prospective study examined patients who underwent surgical resection and had histopathology samples collected, irrespective of age or gender. A comprehensive MRI examination from all perspectives, along with contrast-enhanced images, was conducted. Inclusion criteria encompassed patients of all age groups and genders who had surgery with tissue sample collection for histopathological diagnoses, as well as a complete MRI study including all views and contrast-enhanced images for preliminary diagnosis.
Results: According to senior radiologists' assessments, the most common tumor position was intradural-extramedullary relative to the dura, followed by intramedullary. Despite 20 cases being misdiagnosed, the overall diagnostic accuracy of MRI remained high at 69.2%.
Conclusion: MRI exhibits superior diagnostic accuracy in identifying meningiomas compared to nerve sheath tumors. Additionally, it demonstrates good predictive accuracy for intramedullary lesions such as ependymomas.
Keywords
Astrocytoma, ependymoma, Schwannoma, spinal canal stenosis.
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