Volume 20 No 9 (2022)
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A Prospective Observational Study on Prevalence of Diabetes with Nonalcoholic Fatty Liver Disease in Gastroenterology Department of Tertiary Care Hospital
Sreenu Thalla, R. Kamaraj, A. Kavitha
Abstract
Non-alcoholic fatty liver disease (NAFLD), the majority universal source of hepatic abnormalities with fat accumulation with results in abnormal function of liver may cause change in metabolism. The aim of this study is prevalence of diabetes patients suffering with chronic liver disease as it is observational study. A total of 150 patients who were diagnosed as NAFLD are included in the study in which 71 patients were males and 79 patients were females. Out of 150 patients participated in the study, 106 patients were found to have NAFLD with DM and 44 were NAFLD without Diabetes Mellitus (DM). The highest prevalence was recorded in the age group of >60 years and it was more prevalent among females than males. The majority of the patients were found in the age group of >60 years followed by 40-60 years and least in 20-40 years of age. The patients diagnosed with NAFLD with a duration of >3 years were found in 90 patients followed by 1-3 years in 42 and 0-1 year in 18 patients respectively. The most common Ultrasonography (USG) Abdomen grade of NAFLD was Grade I (73 patients) followed by Grade 2 (58 patients), and least in Grade 3 (16 patients) and Grade 4 (3 patients).Whereas NAFLD patients with DM have elevated prevalence of Non-Alcohoic Steato Hepatitis (NASH) and advanced fibrosis, the probable risk of severe NAFLD cannot be ignored in patients without DM since both NASH and advanced fibrosis occur in a substantial proportion of these patient
Keywords
Chronic Liver Diseases, Diabetes, NAFLD, Steatosis, NASH
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