Purpose and Background: The goal of this study is to examine the efficacy of various medications that are recommended for the treatment of patients in India who are suffering from mild-to-severe cases of corona virus disease 2019 (COVID-19). Methods: In study carried out a retrospective, cross-sectional, observational and descriptive study. Patients diagnosed with COVID-19 ranging from mild, moderate and severe were given as part of this treatment. The primary objectives are to compare the categorical treatment protocols for COVID-19 (as per NIH Treatment Guidelines) infected mild, moderate and severe patients. To evaluate the efficacy of the drugs on the basis of at the time of discharge improvement in SPO2, RR, D-Dimer, PCT, CRP and Ferritin Values. Results: A total of 266 patients included in this study mild to severe COVID 19 infection led to significant improvement in SPO2, Respiratory rate (RR), D-Dimer, Procalcitonin (PCT), C-Reactive Protein (CRP) and Ferritin level. Conclusion: Adult patients with mild, moderate and severe COVID- 19 infection, when treated with different drug combination, were more likely to improve in terms of inflammatory markers and disease severity markers and were more likely to have a better clinical profile at the end of the treatment period

Antiviral, Corona virus, COVID-19, SARS-CoV-2 patients, Retrospective, Cross-sectional, Observational Descriptive study and Categorical treatment