BACKGROUND: Peripheral nerve damage from an initial M. leprae infection causes leprosy. The bacterial index (BI) and the degree of impairment in Pakistani leprosy patients are strongly correlated, despite the fact that disability has a significant influence on patients' quality of life. METHODS:The study methodology employed was cross-sectional retrospective. Medical records of patients with diagnoses of grade 0, 1, or 2 impairments and MB or PB leprosy were sampled using the full sampling procedure. The link between BI and the degree of impairment in leprosy patients was examined using a correlation analysis test. RESULTS: This research comprised 278 individuals in total, of whom 13 (4.7%) had PB leprosy and 265 (95.3%) had MB leprosy. Significant outcomes were attained in 5 of the 9 groups: (A) The hand group in MB+PB leprosy with aprobability value of 0.047, (B) The foot group in MB+PB leprosy with a probability value of 0.002, (C) The foot group in PB leprosy with a probability value of 0.000, (D) Hand group in MB leprosy with a probability value of 0.021, and (E) Foot group in MB leprosy with the probability value of 0.006. CONCLUSIONS: In 56% of the analyzed groups, positive relationships between BI and disability grade were discovered. The findings of recent research may provide therapists with fresh perspectives on how to avoid leprosy-related disabilities.

Leprosy, Paucibacillary, Multibacillary