Objective: The objective of this study was to examine the remission and preservation of hormones, endocrinological and anatomical problems, and visual improvement following endoscopic transsphenoidal surgery (ETS). Methods: This observational study looked back at all cases of pituitary adenoma that had endoscopic transsphenoidal surgery (ETS) performed on them in a single 5-year period. Two hundred patients who had pituitary adenoma and had transsphenoidal surgery were a part of this research. Results: In total, 120 patients had non-functional pituitary adenoma and 80 had functional one. The non-functioning pituitary group had 72 males and 48 females, while the functional group had 44 males and 36 females. Notably, 32 non-functional pituitary adenoma patients were aged 50-59. However, 16 functional pituitary adenoma patients were under 30. Within three months of surgery, 16.66% (n = 20) of non-functioning pituitary adenoma patients reported improvements in eyesight and hormone levels, while 83.34% (n = 100) did not. Twelve patients with cavernous sinus tumors improved their eyesight, while 36 did not. After the operation, 12 individuals had compromised endocrine function, while 36 had normal function. The cohort included 68 acromegaly and 12 Cushing's patients. Conclusion: In order to assess the success of the operation and the patient's well-being, it is crucial to maintain or restore hormonal function. Modern technology, such as endoscopy and magnetic resonance imaging (MRI), has improved surgical outcomes and decreased postoperative complications.

Endoscopy, Pituitary Adenoma, Transsphenoidal Surgery