Anti Hyperlipidemic Activity Of Hydro Alcoholic Extract Of Pterocarpus Marsupium On High Fat Diet Induced Hyperlipidaemia InRats.

Volume 20 No 9 (2022)

Gopichand Babre , Satish Kalshetty S , Shivakumar Inamdar , Ashok Kumar Dastapur

DOI: 10.14704/nq.2022.20.9.NQ44686

Abstract

The aim of present study is Hydroalcholic extract of Pterocarpus marsupium (HAPM) on High Fat diet induced hyperlipidemic rat in models, Here Chronic hyperlipidemia was induced by administration of oral feeding fat diet for 21 days to rats, treat with HDF significantly increased serum blood parameter such as Cholesterol, Triglycerides. Treatment with HAPM 300 and 500 mg/kg, p.o significantly reduced the hyperlipidemia i.e., decreased levels of serum Total Cholesterol, Triglycerides, Low Density Lipoprotein Cholesterol (LDL-C), Very Low Density Lipoprotein Cholesterol (VLDL-C) , increase of serum High Density Lipoprotein Cholesterol (HDL-C) when compared to vehicle control and Atorvastatin (10 mg/kg). Histological study on heart showed amarked regression compare to control The results demonstrated that HAPM possessed significant antihyperlipidemic activity

Keywords

P. marsupium,HDF,HDL and TG

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