Association Of Serum Uric Acid And Ganglion Cell Complex Thickness In Primary Open Angle Glaucoma With Type 2 Diabetes Mellitus

Volume 20 No 7 (2022)

Masitha Dewi Sari,Aryani Atiyatul Amra , Vanda Virgayanti

DOI: 10.14704/nq.2022.20.7.NQ33394

Abstract

Introduction: Diabetes mellitus (DM) is a disease that causes eye complications such as glaucomatous optic neuropathy. In DM, hyperglycemia is known to the increase of uric acid (UA) excretion, which damages the endothelial structure and the tight junctions of retinal blood vessels. In addition, alterations of the extracellular matrix can lead to an increase in trabecular reticular resistance which causes a decreased flow leading to IOP increase and retinal ganglion cells (RGC).

Keywords

Diabetes Mellitus, Ganglion Cell Complex, Primary Open Angle Glaucoma, Uric Acid

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