Association of Interleukin-17A Gene Polymorphism in Ankylosing Spondylitis and Psoriatic Arthritis

Volume 20 No 6 (2022)

Enas Mohammad Mekkawy ,Nahla Mohamed Gaballah ,Eman El-Dessouki El-Shahawy ,HalaAbd ElHameedAbd El-Azeez ,ShaimaaMostafa ABD-El Wahab

DOI: 10.14704/nq.2022.20.6.NQ22936

Abstract

Background: Interleukin-17A (IL-17A) gene is suggested to play a pivotal role in ankylosing spondylitis(AS) and psoriatic arthritis (PsA). Its polymorphism can be considered as a risk factor for AS and PsA susceptibility and its clinical presentation. This study aimed to find the association of IL-17A (rs2275913) single nucleotide polymorphism (SNP) and the risk of both AS and PsA and their clinical manifestations in a cohort of AS and PsA patients

Keywords

:AnkylosingSpondylitis;Psoriatic Arthritis;Interleukin-17A Gene Polymorphism

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