Auditory and Visual Oddball Paradigm Evaluated Through P300 in Five Girls with Rett Syndrome

Volume 17 No 7 (2019)

Rosa Angela Fabio, Tindara Caprì, Caterina Buzzai, Virginia Pittalà, Antonio Gangemi

DOI: 10.14704/nq.2019.17.07.2639

Abstract

Few studies investigated information processing in genetic syndrome, such as Rett Syndrome, using ERPs. The main aim of this study was to examine visual and auditory processes in children with Rett Syndrome through the oddball paradigm. Five children with a diagnosis of Rett Syndrome, ranging from 7 to 11 age (M = 8, 8 years, SD = 4,36), matched for sex, age and mental age to typically developing children. Event-related potentials were recorded to an auditory and visual oddball task in all participants. The results showed that both auditory and visual P300 latencies were longer in the Rett group than the typically developing group. These findings suggest that children with Rett Syndrome need more time to process information.

Keywords

Rett Syndrome, ERP, oddball task, P300

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