Volume 19 No 6 (2021)
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Bioactivity of Some Natural and Semisynthetic Coumarin Derived Compounds
Yasser Fakri Mustafa , Moath Kahtan Bashir , Mahmood Khudhayer Oglah , Raghad Riyadh Khalil , Eman Tareq Mohammed
Abstract
A couple of natural coumarins was identified in the seeds of two apples’ cultivars commonly known as Granny Smith
and Red Delicious. The effect of the phenolic hydroxyl moieties found in these products was evaluated on the
bioactivity. This evaluation included the structural alteration of these moieties into less hydrophilic ones to explore
the significance of the parent moieties on the biological activity. The investigated biopotentials were antioxidant,
antiproliferative, antibacterial, and antifungal effects
Keywords
Natural and Semisynthetic Coumarins, Biological Activity, Phenolic Hydroxyl Moiety, Structural Alteration
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