BACKGROUND To correlate intraocular pressure and central corneal thickness with glycosylated haemoglobin levels in patients with diabetes mellitus. METHOD In this retrospective study, patients meeting the inclusion criteria were evaluated during their visits to the outpatient department of R.L. Jalappa Hospital,Kolar. Detailed histories were collected, encompassing sociodemographic details, occupation, any prior history of ocular surgeries or trauma, history of glaucoma, long-term use of eye drops, or intake of other medications. A comprehensive ophthalmic examination was performed, including assessment of visual acuity, examination of the anterior segment via slit lamp biomicroscopy, and posterior segment evaluation using a 90D lens. Additionally, intraocular pressure was measured using Goldmannapplanation tonometry, blood HbA1c levels were determined, and corneal central thickness (CCT) was assessed using ultrasonographicpachymetry under topical anesthesia. RESULTS 99 participants were included, out of which were 55 (55.55%) males and 44 (44.44%) females. Mean age of the patients was 62.74 + 11.44 years. Out of 99 patients, 43 patients had IOP more than 14.50 mmHg and the average HbA1c levels calculated were 8.95 %. 56 patients had IOP less than 14.5mmHg and HbA1c levels were 7.74 %.There was significant positive correlation between HbA1c and CCT in both eyes of study subjects, with a significant p value of <0.001. CONCLUSION Our results suggest that there is a correlation between the measurement of IOP and CCT, and the levels of HbA1c in patients with diabetes mellitus. Hence, we can say that HbA1c levels can be a good predictor of raised intraocular pressure in diabetes mellitus and can help in early detection of diseases like glaucoma.

Central Corneal Thickness, Diabetes Mellitus, Glycated Haemoglobin, Intraocular Pressure.