Comparative Study of Testosterone, Spironolactone, Docetaxel and Their Combination Effect on Prostate Cancer Cell Line LNCaP

Volume 20 No 6 (2022)

Rawaa A. Alawi AL Khafaji , Entisar J. Hamad AL-Mukhtar , Rana A. Ghaleb

DOI: 10.14704/nq.2022.20.6.NQ22673

Abstract

Background: Prostate cancer is the (most frequent) type of cancer among males. Androgenic hormones have a big role in prostate cancer, which is a kind of glandular malignant neoplasia. Testosterone hormone play important role in the cancer cell propagation) and invasion into (surrounding tissue) by cell migration, which is the first stage in tumor metastasis.

Keywords

Testosterone, Spironolactone, LNCaP cell line, prostate cancer

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