Volume 19 No 2 (2021)
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Comparison between the Effect of Vitamin D Supplementation and Metformin on Insulin Resistance in Women with Polycystic Ovarian Syndrome
Rania Mahfouz Abdel Wahed , Al Shaymaa Abdel Badie Abdel Alim Nasr
Abstract
Background: Women with polycystic ovarian syndrome (PCOS) often lack vitamin D, with a blood 25-
hydroxy vitamin D (25OHD) level of <20 ng/ml seen in 67–85% of PCOS patients. Decreased 25OHD values
were connected to insulin resistance, ovulatory and menstrual anomalies, poor pregnancy efficiency,
obesity, hirsutism, hyperandrogenism, and higher cardiovascular illness risk factors, according to
observational investigations
Keywords
vitamin D, insulin, PCOs syndrome
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