Volume 20 No 20 (2022)
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Correlation of Mast cells and Microvessel densities in TNM staging, Grading and Nodal metastasis of Oral Squamous Cell Carcinoma (OSCC)
Thirumalaraju Kalyani, Dr. Yogesh Yadav, Dr. Anju Lata Rai, Dr. Devicharan Shetty
Abstract
Angiogenesis has been associated with tumor progression and metastasis of various malignancies including oral squamous cell carcinoma (OSCC). Among the host immune cells mast cellsare believed to secrete pro-angiogenic factors that may help in tumor metastasis and invasion. TNMstaging is important for treatment planning, estimating risk of recurrence, and assessment of overall survival of the patient. The aim of the present study was to examine the mast cell and microvessel withTNM staging and Lymph node metastasis in OSCC
Keywords
Tumor node metastasis, Micro vessel density, Mast cell density, Vascular endothelial growth factor
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