Volume 20 No 12 (2022)
 Download PDF
Cytotoxicity of Green biosynthesized selenium nanoparticle on PC3 and WRL 68
Hawraa Jawad Kadhim, and Wijdan Ridha Taj-Aldin
Because of its importance in numerous physiological process , SeNPs research has gotten greater interest in recent years. In comparison to selenium, selenium nanoparticles have a high level of absorption in nutritional supplements . SeNP has been synthesized using a variety of chemical and biological techniques. Because of its anti-oxidant, anti-bacterial, anti-diabetic, and anti-cancer properties, selenium nanoparticles have biological and pharmacological applications . This article reviews biosynthesis of SeNPs using Na2SeO3 and Bacillus clausii under aerobic conditions .The structural and morphological properties of SeNPs were determined by UV_Vis spectroscopy and the absorption peak was observed at ( 260 nm) wavelength , in SEM size range between (37.58 – 75.16 nm) , the average diameter of SeNPs was 19.28 in AFM . Results showed that no significant cytotoxic effect of SeNPs against PC3 cells at concentrations (25 and 50 µg/mL) . Nevertheless, SeNPs at (100, 200 and 400 µg/mL) exhibited a dose_dependent_decrease in PC3 cell viability with maximum inhibition rate of 51.27±2.77% of PC3 cells at 400 µg/mL
SeNPs , Bacillus clausii , UV- Vis spectroscopy , SEM , AFM , PC3 and WRL 68
Copyright © Neuroquantology

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Articles published in the Neuroquantology are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJECSE right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.