


Volume 20 No 10 (2022)
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DEVELOPMENT AND IN-VITRO CHARACTERIZATION OFCATIONICPOLYSACCHARIDE GEL OF MINOXIDIL
Avinash Gupta , Vandana Arora Sethi and Savita Bhati
Abstract
The major concern of topical fabrications is to facilitatively administer API into the area wherever it
is required, consistently on external and manifest dermis membranes and exterior mucosa. Minoxidil
(Rogaine) was initially considered a blood pressure-lowering agent, but over time, it was also
considered hypertrichosis for patients suffering from scarcer trichome problems. To make the
genesis of an ideal fabrication, we must always look for permeation of a formulation where it is
needed and whereby holding of API is vital. Three Formulations were developed as a part of this
study F2, F4 and F6. Amongst the 3 formulations formulation, F2 was found to be most suitable as
per the initial assessment, and also subsequent release studies indicate that formulation F2 can be a
suitable candidate for the management of male pattern baldness.
Keywords
Alopecia CationicPolysaccharide, Gel, Minoxidil, Spreadability Study
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