Volume 20 No 9 (2022)
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DIAGNOSTIC SIGNIFICANCE OF MOLECULAR-GENETIC MARKERS IN THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
Xamrayev A.A., Yuldasheva D.Kh., Jalalova V.Z., Raxmatova M.R., Shamsiyeva T.T., Haydarov D.B
Abstract
Currently, the high growth rate of non-alcoholic
fatty liver disease (NAFLD) is estimated by the
tendency of the population to become obese.
However, as the level of obesity increases, the
severity of the disease also increases. NAFLD
occurs with 30-100% obesity. In NAFLD, most
patients (48-100%) are asymptomatic and are
detected during general examinations. A nonprogressive form of NAFLD - hepatic steatosis
occurs in 40-78% of patients. When the disease
progresses periodically, 12-40% of patients may
develop non-alcoholic steatohepatitis after 8-13
years, and 15% of patients may develop liver
cirrhosis and liver failure. 7% of patients with
liver cirrhosis may develop hepatocellular
carcinoma after 10 years
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