Design and Characterization of Propranolol Hydrochloride Immediate Release Tablets by Response Surface Methodology

Volume 20 No 6 (2022)

Vijayabhaskar Kanakam, Srinivasa Rao Pingali, Venumadhav Neerati and Ravikrishna Velupula

DOI: 10.14704/nq.2022.20.6.NQ22296

Abstract

The goal of the research is to design and optimize Propranolol Hydrochloride immediate-release tablet using response surface methodology. Propranolol Hydrochloride immediate-release tablets used in the treatment of heart attacks, myocardial infarction. Response surface methodology calculations for this optimization study were performed utilizing Minitab 17. Different formulations of immediate-release were prepared by applying 2 factors 3 levels full factorial design using Minitab 17, which gave 9 formulations by using the wet granulation method.

Keywords

Gastrointestinal tract, Myocardial Infarction, Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Immediate Release Tablet.

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