This study was conducted to detect the presence of Helicobacter organism in the oral and gastric mucosa of slaughtered goats at the Anatomy Laboratory of the University of East Philippines - College of Medicine to detect pathological changes in the stomach of Helicobacter-positive goats, and to propose measures and recommendations as well as overall management regarding the public health implications of the spread of Helicobacter. Samples were obtained from three regions of stomach, such as the cardiac, fundus and pylorus, and oral cavity to detect Helicobacter species using Urease Assay and Brush Cytology. Results of the study showed that eighty percent (4/5) of samples reacted positive to urease test. Among the parts of the stomach examined, the pylorus gave the most positive response to the urease test, reaching 80% (4/5), while the cardiac and basal areas scored 60% (3/5). On the other hand, brush cytology and microscopic examinations of Gram and Giemsa-stained slides revealed that Helicobacter bacteria are found in the cardiac and pyloric regions (40% or 2/5) followed by basal regions constituting 20% (1/ 5) and in the oral cavity (60% or 3/5). Further, for the detection method, 60% (3/5) of samples gave positive reaction both for urease and brush cytology. It is recommended that further studies for the detection of Helicobacter be conducted using histopathology and polymerase chain reaction (PCR) assays for conclusive diagnosis and determination of its potential animal-to-human transmission

Helicobacter, urease test, brush cytology, Gram’s and Giemsa staining