Chronic Renal Failure (CRF) is a term used to describe an irreversible decline in renal function that often occurs over a number of years. In many situations, an initial insult to the kidney function leads to additional nephron loss and the requirement for dialysis or kidney transplantation End stage renal disease(ESRD) is the term used to describe this ailment. A number of metabolic, vascular, and inflammatory illnesses are caused by adipokines. In order to determine whether certain associated biomarkers can aid in the diagnosis of CRF patients, this study compares the levels of inflammatory adipocytokines (leptin and adiponectine), as well as their ratios, in ESRD patients and healthy controls

Analyze of serum levels of Leptin and Adiponectin inend-stage renal disease (ESRD)and Healthy individuals.