Hydrogels are macromolecules that are naturally occurring and have unique properties like biocompatibility, cell-controlled degradability, and intrinsic cellular interaction that eventually affect their use in tissue engineering, notably for the development of new tissues. Most of the time, hydrogels facilitate cell migration, angiogenesis, high water content, and enhanced transportation of nutrients. Because of their biochemical resemblance to the skin extracellular matrix, scaffolds have drawn attention and are now recognised as a unique tool for skin tissue engineering concepts. In this study, a Stevioside loaded Pluronic F127/ Agar hydrogel scaffold was designed using the physical cross-linking technique that mirrored the structure and composition of skin extracellular matrix. To achieve the study's primary goal of a composite scaffold that degrades at a controlled rate.

Stevioside, Pluronic F127, Agar, Hydrogel, Skin wound healing.