Objectives-:The aim to evaluate the knowledge of adolescents about adverse effects of substance abuse in selected rural areas, to associate the knowledge score about adverse effects of substance abuse with selected demographic variables and to disseminate an knowledge by structure teaching program regarding adverse effects of substance abuse. Methodology: To achieve the objective of the study Quantitative approach and one group pre-test and post-test design was used. Study was done on 70 adolescents by using Non-probability convenient sampling technique were selected Results: The major finding of the study reveals that mean pre-test knowledge was 8.95 and meanpost-testknowledgescorewas20.12.The calculate‘t’valueis35.81isgreaterthantablevalue2.00at 0.05 level of significance. Hence it is statistically interpreted that structured teaching programon knowledge regarding adverse effects of substance abuse among the adolescents in selectedrural areaswaseffective, Thus H1 accepted andH0rejected Conclusion: The analysis reveals that there is association post- test knowledge score with age inyear, education, religionand occuppation of head of family while none of other demographic variables were associated with knowledge score

Effectiveness,StructuredTeachingProgram,substanceabuse,adolescents,rural areas