Volume 20 No 8 (2022)
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ETIOLOGY AND OUTCOME OF NEONATAL APNEA IN A TERITIARY CARE HOSPITAL
PRITHVI RAJ , ANKIT GUPTA , RAVANAGOMAGAN, PRITHVI RAJ
Abstract
Apnoea is the most frequent type of breathing disorder in neonatal period frequently prolonging
hospitalization and needing cardiopulmonary monitoring. The definition of apnoea has been
changing in the past years due to new findings on its physiopathology. Apnoea typically resolves
before 37 post menstrual weeks in infants delivered after 28 weeks gestation. However, in infants
born before 28 weeks, apnoea frequently persists after term post menstrual age. A total of 104
neonates suffering from apnoeic episodes admitted to our NICU were studied in detail to know
various underlying aetiologies and their outcome. The neonates who fulfilled the following criteria
were selected for the study group. Out of 104 neonates; which formed the study group majority of
neonates are preterm(n=73;70%) and most of apnoeic episodes occurred in day-2 to day-7
oflife(n=77;74.03%). Neonatal sepsis was the predominant cause (n=42;40.3%) observed in the study
group followed by apnoea of prematurity (n=31;29.8%). Apnoeic episode is inversely co-related to
gestational age and birth weight. The mean birth weight and gestational age were 1553.09 +
310.25gm and 32.61+ 1.6 weeks for the infection group and 1138+205.06gm and 29.96+1.8 weeks
for the apnoea of prematurity group.Early recognition by careful observation, assessment of risk and
subsequent therapy will have a good outcome. Hence it is of utmost importance that careful
monitoring, early intervention and follow up care of high-risk neonates, who are more prone for
apnoea as this study supports.
Keywords
Apnoea of prematurity( AOP), neonatal sepsis; prematurity
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