Background: Patients prefer medical expulsion treatment (MET) because it is inexpensive and non-invasive for treating lower ureteric calculi. Among the various options available, Tamsulosin has been extensively studied as an effective MET in other countries. However, its efficacy in our specific population remains a mystery. Aim: Further research is required to determine the effectiveness of Tamsulosin in treating sub-10mm lower ureteric calculi in our patient population. Methods: This research, which was done over ten months from May 2022 to February 2023, included 70 patients with lower ureteric calculi ≤ 10mm in size and involved a randomized controlled trial. Patients were chosen from the emergency room or surgical outpatient department of the Mayo Hospital in Lahore, Pakistan. The Tamsulosin group and the control group were divided up into two groups in the trial using a computer-generated random number generator. To monitor the pace of stone expulsion and the number of analgesics administered, follow-up appointments were planned for one week and three weeks following the first visit. This investigation aims to ascertain the practical utility of tamsulosin in our local patient group as well as the effectiveness of the drug in aiding the transit of lower ureteric calculi. Results: Out of the total 70 patients who volunteered to take part in the experiment, 5 patients—2 from the Tamsulosin group and 3 from the control group—were lost to follow-up. 46 men and 19 women made up the remaining 65 patients. The average size of the stones passed was 6.17 mm and 6.03 mm, respectively, despite Tamsulosin being administered to one group and receiving no treatment in the control group (p=0.724). Although the percentage of stone passing was somewhat greater in the Tamsulosin group (54.54%) compared to the control group's rate of 43.75% (p=0.384), it was not statistically significant. Also, there was no discernible difference in the average quantity of analgesic (Tab.Diclofenac) consumption between the two groups, with the Tamsulosin group eating 563.32 mg and the Control group taking 637.5 mg (p=0.121). Despite the fact that the results showed no statistically significant difference, they nonetheless provide important details concerning the usage of Tamsulosin in our local patient group and may help shape future medical choices. Conclusions: The utilization of tamsulosin as a medical expulsive therapy for lower ureteric stones may not be as effective as previously believed. This study suggests that alternative treatment options may need to be considered for individuals with this condition.

ureteral calculi, tamsulosin, kidney