Effect of Moringa Olefiera Extract on Erythrocyte Sedimentation Rate And SF-36 Scores In Aromatase Inhibitor-Associated Musculoskeletal Syndrome Breast Cancer Patients

Volume 20 No 18 (2022)

Agung Hartanto, Yan Wisnu Prajoko, Hardian, Trilaksana Nugroho, Yora Ninndita

DOI: 10.48047/NQ.2022.20.18.NQ88072

Abstract

Aromatase inhibitors (AIs) are key components in chemoprevention and treatment of hormone receptor-positive (HR+) breast cancer. AIs are associated with musculoskeletal adverse effects known as the aromatase inhibitor-associated musculoskeletal syndrome (AIMSS), in which the estrogen levels decrease. One of the effects of estrogen is anti-inflammatory. The mechanism of this anti-inflammatory effect is by reducing the synthesis of inflammatory cytokines. Moringa oleifera is a traditional plant that contains glucosinolates, which when hydrolized will produce a component called isothyosianates

Keywords

Moringa olefiera, Aromatase Inhibitor, AIMSS, ESR, SF-36

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