Effectiveness of Hyperbaric Oxygen Therapy forthe Management of Drug-Induced Osteomyelitis

Volume 20 No 4 (2022)

Mohamed Refaat Omar, Fatma Ibrahim Mohamed , Hassan Gamal Sadek , Fatma Wageeh Attaia , Ahmed Mohamed Abdelkader , Mostafa Mohamed, Emadeldin Saad Mohamed

DOI: 10.48047/NQ.2022.20.4.NQ22328

Abstract

Objectives: This Study evaluates the effectiveness of hyperbaric 02 therapies as an adjunctive measure for the management of Bisphosphonate associated jaw Osteomyelitis (BJOM). Methods: Retrospective Study on 18 patients diagnosed with BJOM (2019-2020) and all of them had been Treated with antibiotics, surgery and hyperbaric O2. Results: BJOM was found in 13 of 18 (70.1%) after intravenous bisphosphonate Therapy and 5 of 18 (29.9%) after oral bisphosphonate. Hyperbaric O2 was given for all the cases. About 14 of 18 (76.3%) were cured completely while 4 (24.1%) failed. Clinical Failure defined as, a persistent infective or relapse. Conclusions: Bisphosphonate Therapy is now a frequent cause of jaw osteomyelitis. Hyperbaric O2 is an affective adjunctive treatment modality for the management of BJOM with antibiotics and surgery

Keywords

Hyperbaric Oxygen Therapy, drug- Induced Osteomyelitis.

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