Volume 20 No 8 (2022)
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Efficacy of plain bupivacaine and hyperbaric bupivacaine in spinal anesthesia for elective cesarean section(Randomized control trials)
Salah Mohamed Mansour, Zeinab Abdo Ibrahim Mohammed
Abstract
Objective. Bupivacaine is a frequently utilized local anesthetic for spinal anesthesia, typically administered as a basic solution or a hyperbaric mixture. The ideal solution usage for regional intrathecal anesthesia preferable to has rapid onset & consistent duration, with fewer incidence of unpleasant effects.
Methods. Sixty patients who underwent cesarean section surgeries have been randomized into both groups. Group isobaric bupivacaine IB (number= thirty patients) received plain bupivacaine 10 mg + 20 mcg fentanyl. Group hyperbaric bupivacaine HB (n= 30 patients) hyperbaric bupivacaine 10 mg + 20 mcg fentanyl in spinal anesthesia for optional cesarean sections. Injection has been made intrathecally in sitting position or left lateral approach at L3-4 interspace.
Results: the commencement of motor blocks with hyperbaric bupivacaine has been sooner (1.8-± 0.6) when assessed versus to isobaric (4.0 ± 1.33) minutes, respectively. The period of motor & sensory blocks has been longer in hyperbaric bupivacaine (201.03 ± 19.694) minutes when compared to isobaric bupivacaine (136.91 ± 12.81) minutes. In both groups, no significant differences in hemodynamic & the adversarial effects have been equivalent.
Conclusion: hyperbaric bupivacaine created more fast commencement & lengthier period when assessed to Isobaric but a good alternative.
Keywords
spinal anesthesia, plain bupivacaine, hyperbaric bupivacaine, elective cesarean section
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