Objectives: It is still necessary to evaluate the antibacterial potential of medicinal plants, which could result in the development of broad-spectrum antimicrobial molecules. In underdeveloped nations; traditional medicine is one of the most widely accessible forms of treatment. Objective of present study was evaluation of the antimicrobial activity of the stem bark extracts of Bridelia micrantha against MDR salmonella typhimurium Methods: In this study, the agar-well diffusion method was used to test the antibacterial activity of Bridelia micrantha stem bark extract of Bridelia micrantha and chloramphenicol against MDR Salmonella typhimurium. Results: Brielia micrantha's crude extract was found to be effective against MDR salmonella typhimurium. The crude extract of Bridelia micrantha was shown to have minimum inhibitory concentration (MIC) and zone of inhibition values of 1.25 mg/ml and 17.50 ±0.50 mm to 23.50 ±0.00 mm, respectively. Conclusions: The results of this study show that Bridelia micrantha's crude extracts have In-vitro antibacterial activity, which serves as preliminary scientific support for the plant's usage in treating MDR infections.

Minimum inhibitory concentration, Salmonella Typhimurium, Multidrug resistance, Bridelia micrantha, zones of inhibition.