Flow chemistry has emerged as a powerful and versatile tool in chemical synthesis, offering numerous advantages over traditional batch processes. This review explores the advancements and applications of flow chemistry, focusing on its impact in various fields such as pharmaceuticals, material science, and green chemistry. The historical development of flow chemistry is discussed, highlighting key milestones and contributions that have shaped the field. The principles of flow chemistry, including fundamental concepts and types of flow reactors, are explained, emphasizing the differences from batch chemistry and the advantages of continuous flow systems. The review also covers recent advancements in flow chemistry, such as the continuous flow synthesis of pharmaceuticals, applications in material science, and the integration of green chemistry principles in flow systems. Additionally, the paper discusses the applications of flow chemistry in organic synthesis, the pharmaceutical industry, fine chemicals, and bioconjugation. Challenges and future perspectives of flow chemistry, including scalability, automation, and multistep synthesis, are also addressed. Overall, flow chemistry has the potential to revolutionize chemical synthesis, offering a sustainable and efficient approach to chemical manufacturing.

flow chemistry, continuous flow, pharmaceutical synthesis, material science, green chemistry, organic synthesis, automation, multistep synthesis