FORMULATION AND EVALUATION OF NEEM GUM NIOSOMAL GEL FOR THE TREATMENT OF PERIODONTITIS

Volume 20 No 10 (2022)

Mohit Singh, Prof. (Dr.) Sachin Kumar

DOI: 10.14704/nq.2022.20.10.NQ55776

Abstract

Periodontitis is an inflammatory condition of teeth's supporting tissues due to specific pathogens. Antibiotic delivery has already been studied in a bid to overcome the drawbacks of standard treatments. The purpose of this research is to prepare niosomes, which are then constructed into niosomal gels. Coacervation phase separation was used to create the preparation. Entrapment efficiency, vesicle size, surface morphology, and in in vitro drug release were all measured in prepared formulation. Carbopol 934P and neem gum were used as gelling agents in the preparation of the niosomal gel formulation

Keywords

Herbal, Niosomal gels, Antibiotic, Periodontitis

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