Volume 19 No 4 (2021)
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FORMULATION DEVELOPMENT AND EVALUATION OF ORODISPERSIBLE TABLETS OF NIFEDIPINE HCL
Vaibhav Kumar Jagtap
Abstract
The enhancement of dissolution rate and oral bioavailability of poorly soluble drugs remains one of the most challenging aspects of drug development. Among the various methods of enhancement of the dissolution rate and oral bioavailability, various disintegrating agent was used and successful with a number of drugs. In the present investigation, studies were carried out on a new class of tablet excipients called “ Super Disintegrants” was used for enhancing the dissolution rate of poorly soluble drugs. In the present investigation orally disintegrating tablets of nifedipine was formulated and evaluated.
Keywords
Disintegration, Nifedipine, Evaluation
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