spray dry methods for formulation of microspheres to deliver medications have numerous other benefits over one another, including controlled drug release, increased bioavailability, and targeted drug delivery to the desired place. In order to achieve the required therapeutic effect, this research demonstrates the usage of encapsulating sodium alginate and sodium carboxy methyl cellulose in biodegradable microsphere delivery system, to be administered orally via a capsule. The benefit of microsphere formulations over traditional tablet or capsule formulations are that they increase the surface area exposed to the absorption site, boosting medication absorption and reducing drug dose frequency. An non-steroidal anti-inflammatory drug called flurbiprofen is used to treat infections and intestinal diseases such ulcerative colitis, Crohn's disease, and carcinomas. Flurbiprofen has a half-life of 4 hours, a poor bioavailability when taken orally, and its highest absorption occurs in the lower gastrointestinal system. The production yields, actual drug content, encapsulation effectiveness, percentage Swelling Index, in vitro release analysis, mucoadhesive strength assessment, and in vivo procedures of the microsphere formulations were all assessed.

Microsphere, Mucoadhesive, Flurbiprofen