Formulation, development and evaluation of Atorvastatin calcium loaded nanosponges (ATRCNSGs) by using factorial design and its in vivo study

Volume 19 No 11 (2021)

Raju Balaji Reddy, Vinod Nakra , Manmeet Singh Saluja

DOI: 10.14704/nq.2021.19.11.NQ21236

Abstract

Introduction: Atorvastatin calcium is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate- limiting enzyme that converts 3-hydroxy-3-methyl-glutaryl- coenzyme A to mevalonate, a precursor of sterols, including cholesterol

Keywords

Atorvastatin calcium, nanosponges, ICH guidelines, in-vivo pharmacodynamic study, TG, TC, LDL

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