In the present study, Aceclofenac emulgel formulation was successfully develops to improve patient compliance by lowering the gastrointestinal and other systemic-side effects. Five Emulgel formulations (F1-F5) with different concentration of gelling agent carbopol 934 were prepared. Formulation developed (F1-F5) shows acceptable physical properties like appearance, Consistency, extrudability and viscosity. Drug content of all formulations were also within limits. In-Vitro release test were also carried out using phosphate buffer pH 7.4 as receptor medium. Release study indicated drug release form the formulations with varying concentration of polymers. Formulation F4 shows maximum drug release i.e. 99.53±0.12% in 24 hours and was selected as the best optimized formulation. Formulation found to be stable with respect to physical appearance, pH and drug content at all temperature and condition for 1 month. Hence Emulgel of Aceclofenac is one of the better

Diffusion, Drug content, Permeability enhancer, Stability, Emulgel