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Volume 20 No 7 (2022)
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Formulation and Evaluation of Curcumin Loaded Gel Embedded Beads for Solubility Enhancement
Rajeev Yadav, Lokesh Kumar Jha, Dr. Pushpendra Jain, Prabha Singh, Dr. Vivek
Abstract
Curcumin is a tautomeric complex that exists in the form of enolic in natural diluters & in water as a
keto form. Natural pigment present in the Curcumin which containing anti-fungal, anti-bacterial, antiviral, anti-inflammatory, anti-malarial, anti-oxidant, anti-mutagenic agent, abilities of wound healing &
enhances anti-tumor property in contradiction of various types of tumor cells but curcumin is very
poorly soluble in water which leads to an very low oral bioavailability.
Keywords
Sodium Alginate (SA), Calcium Chloride (CaCl2), Curcumin, Microbeads, CB (Curcumin beads).
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