Volume 20 No 6 (2022)
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HEPATOPROTECTIVE ACTIVITY OF TURNERAAPHRODISIACA LEAVES AGAINST PARACETAMOL INDUCED LIVER INJURY IN RATS.
Naveen Kumar Bathula, Bimalendu Chowdhury
Abstract
Objective: The present study is done to evaluate the Hepatoprotective activity of Ethanolic extract of Turnera aphrodisiaca leaves against paracetamol-induced liver damage in male Wistar rats. Methods: Rats were divided into five different groups each having six. Group 1 served as a Normal control, Group 2 received paracetamol (2gm/kg, oral), in sterile water, Groups 4 and 5served as extract treatment groups and received a dose of 200 mg/kg, and 400 mg/kg, orally, Ethanolic extract of Turnera aphrodisiacaleaves (EETA) and Group 3 served as standard group and received silymarin at a dose of 25 mg/kg orally, treatment protocols followed sevendays, and after which rats were sacrificed, the liver was taken for biochemical and histological studies, respectively
Keywords
Paracetamol, Ethanol, Turnera aphrodisiaca, Hepatoprotective, EETA
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