Hazardous Genomic Bioeffects of Home Wi-Fi Systems

Volume 16 No 11 (2018)

Sevgi Durna Dastan , Sinan Soylu , Halime Hanım Pence , Bülent Uyanik , Mustafa Duman , Atilla Kurt , Taner Dastan , Aydin Zilan , Mustafa Turan

DOI: 10.14704/nq.2018.16.11.1190

Abstract

Objective of this study is to investigate the changes of whole genom gene expression levels in rat brain induced by 2,4 GHz Wireless Fidelity Radiofrequency Electromagnetic Field (WiFi RF-EMF). Total RNA was extracted immediately and purified from the rat brain, after 12 hours/day exposed or sham-exposed to a frequency of 2,4 GHz WiFi RF-EMF for 14 days. Roche-Nimblegene-Agilent Microarray System was applied to investigate the changes of gene expression in rat brain. Roche-Nimblegene-Agilent Genespring Software for Microarray Analysis was used in bioenformatic analysis. After 14 days of WiFi RF-EMF exposure, 69 genes in experimental group showed statistical significant down regulation compared with the control group. Ten genes in experimental group showed statistical significant up regulation compared with the control group. In this study, it was detected that WiFi RF-EMF exposure to brain cells resulted with the down and up regulation of transcription level of some important genes

Keywords

Wireless Radiofrequency, Electromagnetic Field, Gene Expression, mRNA

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