Heteropoly acid (PW/SiO2) Catalyzed Environmentally Benign Synthesis of 4-Thiazolidinone Derivatives

Volume 20 No 9 (2022)

Dadabhau A. Kharat, Mazahar Farooqui, Madhav J. Hebade, Bhagwansing S. Dobhal

DOI: 10.14704/nq.2022.20.9.NQ44786

Abstract

A silica-supported phosphotungstic heteropoly acid (PW/SiO2) promoted cyclocondensation-cyclization pathway has been established using one pot reaction of anilines, aldehydes and mercaptoacetic acid to give 4-thiazolidinone derivatives in good to promising yields using microwave irradiation. Application for this protocol easy workup, high yields, short reaction times, variability of functional groups, recyclability and solvent-free conditions.

Keywords

Heteropoly acid (PW/SiO2), Environmentally benign, Multicomponent reactions, 4- Thiazolidinones,

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