Hymecromone and Its Products as Cytotoxic Candidates for Brain Cancer: A Brief Review

Volume 18 No 7 (2020)

Yasser Fakri Mustafa , Noora Thamer Abdulaziz

DOI: 10.14704/nq.2021.19.7.NQ21101

Abstract

Brain cancer is the 10th cause of death among patients suffering from cancer worldwide. Despite the huge effort put out to extract, design, and synthesize novel chemotherapeutic drugs, medicinal chemists continue to face significant obstacles due to considerable side effects, growing tumor resistance, and poor selectivity. In recent decades, great attention has been paid to the anti-cancer potential of a variety of natural compounds. Coumarin-based compounds, for example, are distinguished by their structural variety and wide range of pharmacological characteristics.

Keywords

Brain Cancer, Hymecromone, Derivatization, Synthetic Coumarins, 7-hydroxy-4-Methylcoumarin

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