Volume 20 No 12 (2022)
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INFLUENCE OF ALKALOIDS OF THE PLANT ANABASIS APHYLLA L. ON THE PHYSIOLOGICAL PROCESSES OF ANIMALS
MirzaevSaidmakhmud, ImomovOtabekNormirzoyevich
Abstract
The article provides an assessment of the effect of the activity of the alkaloids anabasine, anabasamine and lupinine in various doses on apomorphine hypothermia in mice and rats, as well as a study of apomorphine hypothermia in rats as a test for psychotropic drugs and studied the effects of these alkaloids in various doses on physical activity and body temperature of animals. An assessment of the influence of the activity of alkaloids at various doses on the physical excitation induced by phenamine in mice was studied. We analyzed that alkaloids, like antidepressants, significantly counteracted the effects of reserpine and phenamine, but their effect was less pronounced than that of imipramine, and alkaloids reduce physical activity and reduce body temperature. These alkaloids act on adrenergic processes. Decreased phenamine arousal and increased phenamine hyperthermia and group toxicity in mice.
Keywords
alkaloids, anabasine, anabasamine, lupinine, physical activity, temperature, hyperthermia, hypothermia, locomotion, standing up, phenamine, caffeine, Anabasis aphylla L.
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