Objective: Vitamin D deficiency has been linked to several autoimmune illnesses, which may alter the frequency and severity of these diseases. A lack of vitamin D has been identified as a possible contributor to the onset or worsening of autoimmune disease. This study's main objective was to determine the prevalence of low vitamin D levels among people with pemphigus vulgaris. Methods: 76 participants with pemphigus vulgaris, aged 20 to 50, of either gender, were included in the research. Participants who had diabetes mellitus, chronic liver disease, acid peptic illness, or chronic kidney failure were excluded. Blood samples from the patients were collected, and the pathology division of the facility received them for vitamin D testing. Results:The patients in the research had an average age of 34.54 years, with a standard deviation of 6.70 years. 47 patients (61.84%) out of the total number of patients were between the ages of 20 and 35. 39 (51.32%) of the 76 patients were men, and 37 (48.68%) were women, making the male-to-female ratio 1.1 to 1. The patients' illness lasted an average of 6.41 months on average, with a standard deviation of 2.48 months. With a standard variation of 4.57 kg/m2, the average body mass index (BMI) was 26.19 kg/m2. While 21 patients (27.63%) did not exhibit any vitamin D insufficiency, 55 patients (72.37%) were determined to be deficient in it. Conclusions:It has been shown in this study that a large proportion of people with pemphigus vulgaris have a considerable vitamin D deficit.

vitamin D, pemphigus vulgaris, autoimmunity