Volume 20 No 22 (2022)
 Download PDF
In-Vivo Anti-Arthrhitic Activity Of Polyherbal Formulation Containing Maharasnadighan, Ocimum Sanctum Leaves And Nyctanthes Arbor Tritis Leaves Extract
Basant Khare, Tarkeshwar Prasad Shukla, Neetesh K Jain
Inflammation plays an important role in the pathogenesis of RA. Proliferation of synovial cells causes swelling of the synovium that leads to cartilage destruction and thus soft tissue swelling is an important indicator of the underlying disease. In adjuvant arthritis, development of chronic inflammation causes release of biochemical mediators that cause pain, bone destruction, cartilage damage that leads to severe disability. The inflammation/ oedema caused in the paw of the arthritic rats were studied to understand the severity of the disease, its inhibition proportional to the anti-inflammatory activity of the drug. Thus, body weight changes, paw oedema and arthritis scores are common appropriate indicators that may be used to establish the anti-arthritic efficacy of drugs in this model. Polyherbal gel formulation showed significant reduction of paw swelling as compared to the standard drug. Highest inhibition was expressed by Polyherbal gel formulation which was found to be comparatively greater than standard treated group. This studies confirms the anti-arthritic, and anti-inflammatory role of prepared polyherbal gel formulation which have a greater potency to attenuate diseases progression.
Anti-Arthrhitic, Polyherbal formulation, Herbal Medicines, Anti-Inflammatory etc.
Copyright © Neuroquantology

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Articles published in the Neuroquantology are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJECSE right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.